Score for the Prediction of Mortality Risk After Surgery for Colon Cancer in a Case Series of Elderly Patients
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 385
- 试验地点
- 2
- 主要终点
- New surgical score using preoperative parameters to predict 30-day mortality after colon cancer surgery in the elderly population
研究概览
简要总结
CR-POSSUM is one of the most used surgical scores to predict mortality after colorectal surgery. Its main drawback is the requirement of intraoperative variables, whose collection is time-consuming and prevents from obtaining a purely preoperative risk assessment. The primary aim of the study is to develop a new surgical score using preoperative parameters to predict 30-day mortality after colon cancer surgery in the elderly population. The secondary objective is to analyze its efficacy compared to CR-POSSUM.
详细描述
Patients aged 80 and older undergoing surgery for colon cancer from 2011 to 2017 in an Italian hospital were retrospectively selected. MECC score [Mortality in Elderly patients with Colon Cancer] was calculated summing up the scores relating to: arterial saturation of O2, Systolic Blood Pressure, Heart Rate, WBCs, Albumin, Creatinine. Once CR-POSSUM was calculated, the two scores were compared.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 80 Years 至 —（Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients aged 80 and above having elective and emergency colonic resection for colon cancer via open, laparoscopic and converted approaches
排除标准
- •Surgical resections for rectal cancer and surgical procedures for non-neoplastic colon pathologies
结局指标
主要结局
New surgical score using preoperative parameters to predict 30-day mortality after colon cancer surgery in the elderly population
时间窗: Up to 30 days after surgery
MEC Score (arterial saturation of O2, Systolic Blood Pressure, Heart Rate, WBCs, Albumin, Creatinine) for the evaluation of the risk of in-hospital mortality occurred during hospitalization up to 30 days
次要结局
未报告次要终点
研究者
Marialuisa Lugaresi
Adjunct Professor MD, PhD
University of Bologna