Effect of Aerobic Exercise with Blood Flow Restriction on Post-exercise Hypotension in Young Adults: the Role of Histamine Receptors
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 10
- 试验地点
- 2
- 主要终点
- Post-exercise hypotension before and after the histamine blockade
研究概览
简要总结
It was hypothesized that aerobic exercise with blood flow restriction (BFR) induced post exercise hypotension (PEH), and the reduction in blood pressure (BP) was due to peripheral vasodilation via the histamine receptors. Ten male participants participated in this study. The participants were randomly assigned to walk for 10 minutes at 6.4 k/m, 0% grade with or without BFR after taking histamine receptor blockade. Following exercise, BP was measured at 10 min interval for 60 minutes. Heart rate (HR), stroke volume (SV), cardiac output (CO), mean arterial pressure (MAP), and total peripheral resistance (TPR) were evaluated.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Basic Science
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 30 Years（Adult）
- 性别
- Male
- 接受健康志愿者
- 是
入选标准
- •good health,
- •nonsmokers
- •those not taking medications that could affect cardiovascular function
排除标准
- •hypertension
- •muscular skeletal disorder
结局指标
主要结局
Post-exercise hypotension before and after the histamine blockade
时间窗: 10 min, 20 min, 30 min, 40 min, 50 min, and 60 min post exercise
Blood pressure change during 60 min (10 min interval) after BFR exercise
次要结局
未报告次要终点
研究者
Jong-Kyung Kim
Professor
California Baptist University