Relationship Between Exposure to Phenols and Pregnancy Outcomes After Embryo Transfer
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 1,200
- 试验地点
- 1
- 主要终点
- Rate of clinical pregnancy patients
研究概览
简要总结
The goal of this observational study is to explore the association between phenol exposure and pregnancy outcome after embryo transfer. The main question it aims to answer [is/are]:
Whether exposure to phenols is associated with adverse pregnancy outcomes in pregnant women undergoing assisted reproductive technology?
详细描述
First of all, paper questionnaires were used in this study, including general information questionnaire, health effect questionnaire, health survey summary form, and dietary assessment questionnaire. Secondly, obtain the relevant information of the medical record system, including: assisted reproduction protocol, IVF examination results, B-ultrasound examination results, laboratory test indicators, pregnancy outcome information and newborn information. Finally, urine samples were detected using a high performance liquid chromatography mass spectrometer.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 20 Years 至 —（Adult, Older Adult）
- 性别
- Female
- 接受健康志愿者
- 是
入选标准
- •Chinese citizens over the age of 20;
- •IVF/ICSI assisted reproductive treatment in our center;
- •Complete clinical data, reproductive outcomes and questionnaire data of both sexes;
- •Knowing about this research and voluntarily accepting this research;
排除标准
- •The patient receives sperm or egg donation treatment;
- •The patient gave up the egg collection operation due to various reasons, and the cycle was canceled;
- •The patient abandons treatment before achieving clinical pregnancy, but the fertile frozen embryo is not transferred;
- •There are contraindications to pregnancy, such as serious liver and kidney diseases, malignant tumors, serious mental diseases, uncorrected coagulation function abnormalities or endocrine indicators abnormalities;
- •Incomplete or missing clinical data or follow-up data;
结局指标
主要结局
Rate of clinical pregnancy patients
时间窗: From the date of randomization until the termination of pregnancy
Rate of biochemical pregnancy, clinical pregnancy and post-natal patients
次要结局
- Rate of the health newborn(From the date of randomization until the termination of pregnancy)
研究者
keqin liu
Principal Investigator
Tongji Hospital