Incidence, Risk Factors and Outcome of Empyema Following Pneumonectomy for Non Small Cell Lung Cancer (NSCLC)
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 600
- 试验地点
- 1
- 主要终点
- Overall survival
研究概览
简要总结
Empyema following pneumonectomy for Non Small Cell Lung Cancer (NSCLC) is a known problem that occurs in about 2% of pneumonectomy patients.
详细描述
The development of an empyema following pneumonectomy is a devastating complication, especially if associated with an underlying fistula. Whilst the perioperative mortality of pneumonectomy overall is now less than 5%, this rises to around 25% when complicated by empyema, and about 50% when associated with fistula. In addition, there is the morbidity and social cost of long-term drainage, chronic sepsis and often multiple operations.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Pneumonectomy for NSCLC
排除标准
- •Pneumonectomy for other reasons (infectious pathology, trauma, mesothelioma, ...)
结局指标
主要结局
Overall survival
时间窗: 5 years from surgery
overall 5-year survival after empyema following pneumonectomy
次要结局
- incidence rate(1 and 5 years from surgery)
研究者
Johnny Moons
Datamanager Thoracic Surgery
University Hospital, Gasthuisberg