Cortisol secretory pattern between deep neuromuscular block and moderate neuromuscular block in Total laparoscopic hysterectomy patient under anesthesia with total intravenous anesthesia (TIVA) using propofol and remifentanil

Cortisol and ACTH levels were higher at T1 (end of surgery) and T2 (1.5 h after the surgery) than at T0 (before the surgery) in both the groups, but no significant difference was observed between the two groups . Serum glucose level and MAP increased during the surgery (T1) and decreased after the surgery (T2), but no significant intergroup difference was observed . After the surgery, the surgical site pain NRS scores and fentanyl requirement in the PACU were comparable between the groups, and no intergroup difference was observed in hospital stay. However, episodes of additional administration of neuromuscular blocking agents at the surgeon’s request or sudden patient movement during surgery were significantly more frequent in group M than in group D (8/34 vs. 0/33). Conversely, after the surgery, the surgeon’s satisfaction with the surgical field was higher in group D than in group M (P < 0.001).