A controlled clinical study to evaluate the add on effect of Brihat Shatavari Ghrita as Prathimarsha nasya in the management of Premenstrual syndrome vis-a-vis Pittavruta vyana vata
试验速览
- 阶段
- 3 期
- 状态
- 尚未招募
- 发起方
- 入组人数
- 50
- 试验地点
- 1
- 主要终点
- To evaluate the add on effect of Brihat Shatavari Ghrita as Prathimarsha Nasya over Punarnavadi Kashaya and Ashwagandha Churna in Premenstrual Syndrome
研究概览
简要总结
Premenstrual syndrome (PMS) refers to a complex of cyclical and recurrent physical emotional and behavioral symptoms that occurs specifically in the luteal phase and remain for minimum three consecutive menstrual cycles
In India a range of 14.3% to 74.4% is the reported prevalence estimate of PMSIn Ayurveda PMS can be related to Pittavrita vyana vata which is an Avaranajanya Vyadhi. Rituvyatheetha kala is compared mainly with luteal phase there is Pittakopavastha and Vata sanchayavastha. With excessive intake of Pittakara nidana in Rituvyatheethakala Sanchita vata specifically Vyana vata gets Avrita with Kupita pitta and manifested in the form of Sarvanga daha Klama Santapaetc
As per contemporary system of medicine management available for this condition is Antidepressants (SSRIs) NSAIDs diuretics and hormonal contraceptives. These can cause nausea sleep problems drowsiness etc.
The disease PMS can be managed and treated on the line of Pittavrita vyana vata so as to provide relief from its deleterious effects and improve ones family and social life.
In classics the treatment for Pittavrita vyana vata includes Jeevaneeya gana drugs
Brihat Shatavari Ghritacontains Jeevaneeya gana drugs which is Balya Agnivardhakadoes Shamana of Angadaha Raktapitta Vatarakta Paithika Jwara. Ghrita is Vatapitta shamaka. Shatavari has Rasayana effectMedhya Tridoshashamaka Agnibalavardhakawhichcounteract the PMS vis a vis Pittavrita vyana vata.
Pratimarsha nasya is one among Dinacharya procedures which is helpful in promotion of health. It shows action on regulation of endocrine system and nervous system functions. As PMS is a physiological condition Brihat Shatavari Ghrita can be given as Prathimarsha nasya for promotion of health.
Therefore considering the above information this study is planned to evaluate the effect of Brihat Shatavari Ghrita as Pratimarsha nasya in PMS.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 盲法
- None
入排标准
- 年龄范围
- 16.00 Year(s) 至 30.00 Year(s)（—）
- 性别
- Female
入选标准
- •Subjects diagnosed based on diagnostic criteria (Premenstrual Syndrome Scale) Subjects having regular menstrual cycle (21-35 days).
排除标准
- •Any diagnosed clinical condition that interferes with the clinical trial Subjects under hormonal treatment.
结局指标
主要结局
To evaluate the add on effect of Brihat Shatavari Ghrita as Prathimarsha Nasya over Punarnavadi Kashaya and Ashwagandha Churna in Premenstrual Syndrome
时间窗: 21-35 days (after 1st menstrual cycle)
次要结局
- To evaluate the combined effect of Brihat Shatavari Ghrita as Prathimarsha Nasya over Punarnavadi Kashaya and Ashwagandha Churna in Premenstrual Syndrome(21-35 days (after 1st menstrual cycle))
研究者
Dr Hitha M K
Government Ayurveda Medical College and Hospital, Mysuru