跳至主要内容
临床试验/NCT04862728
NCT04862728Unknown不适用

Role of Various Nutritional Interventions in Management of Critically Ill Child

Assiut University0 个研究点目标入组 100 人开始时间: 2021年6月最近更新:
适应症

试验速览

阶段
不适用
入组人数
100
主要终点
Identifying high risk group of malnutrition among patient in PICU by nutritional assesement by Screening Tool for the Assessment of Malnutrition in Pediatrics.

研究概览

简要总结

  • Assess the nutritional status of critically ill children using different nutritional assessment tools in management.

  • Assess accuracy and validity of screening tools in diagnosis of malnutrition by the following:

  • Strong kids

  • Stamp

  • PYMS

  • Assess the effect of early versus late enteral nutrition on the outcome and predict the complication associated with enteral feeding.

详细描述

Malnutrition affects millions of children throughout the World. According to ESPEN nutritional risk screening tools have been designed to detect protein and energy under nutrition and predict if under nutrition may develop or worsen. The Screening was validated Tool for Assessment of Malnutrition in Pediatrics (STAMP) that evaluates patient's clinical diagnosis, nutritional intake during hospitalization and anthropometric measurements, developing a care plan based on the child's overall malnutrition risk. The Screening Tool for Impaired Nutritional Status and Growth (STRONG kids) consists of four items: clinical assessment, high-risk diseases, nutritional intake and losses, weight loss or poor weight gain.

The Pediatric Yorkhill Malnutrition Score (PYMS) is adopted among patients between 1 and 16 years of age assesses four items: BMI, history of recent weight loss, changes in nutritional intake and the expected effect of current medical condition on patient's nutritional status.

Indirect calorimetry, calculated from analysis of the inspired and expired gases, is the best method for evaluating individual energy expenditure.

Protein requirements are highe. The catabolic effects of illness lead to negative nitrogen balance. Randomized protein-supplemented enteral diet achieved 3.1g/kg/day protein and positive nitrogen balance by PICU day 5.

Enteral nutrition is more physiological, simpler, can be started more quickly and cheaper, it does not require special preparation, and it can be started and modified at any time.

研究设计

研究类型
Observational
观察模型
Other
时间视角
Prospective

入排标准

年龄范围
1 Year 至 5 Years(Child)
性别
All
接受健康志愿者

入选标准

  • Critically ill children aged 1-5 years admitted to PICU.

排除标准

  • Infants before the age of one year and children after the age of five years.
  • Any child with chronic illness.
  • Patients with multiorgans failure.
  • Children with congenital anomalies.
  • Children on renal dialysis.

结局指标

主要结局

Identifying high risk group of malnutrition among patient in PICU by nutritional assesement by Screening Tool for the Assessment of Malnutrition in Pediatrics.

时间窗: baseline

Screening Tool for the Assessment of Malnutrition in Pediatrics evaluates patient's clinical diagnosis nutritional intake during hospitalization and anthropometric measurements malnutrition risk. the measured value of the child's height and weight will recorded and compared to reference values by age. and gender

Identifying high risk group of malnutrition among patient in PICU by nutritional assesement by Screening Tool for Impaired Nutritional Status and Growth in kids.

时间窗: baseline

Screening Tool for Impaired Nutritional Status and Growth (STRONG kids) consists of subjective clinical assessment high risk diseases nutritional intake and losses. weight, poor weight gain Patients classified at high nutritional risk have a longer hospitalization and a negative standard deviation score for weight for height which indicated a state of acute malnutrition,this tool appeared rapid and easy to use, additionally it may predict long of hospital stay and identifies a need for nutritional interventions during the hospitalization.

Identifying high risk group of malnutrition among patient in PICU by nutritional assesement by The Pediatric Yorkhill Malnutrition Score.

时间窗: baseline

The Pediatric Yorkhill Malnutrition Score (PYMS) is adopted among patients between 1 and 16 years of age. It assesses BMI history of recent weight loss changes in nutritional intake and the expected effect of current medical condition on patient's nutritional status

次要结局

  • the importance of early versus late enteral nutrition for patient in PICU.(baseline)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Hanan Saad Ahmed Hamdallah

principle investigator

Assiut University

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