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临床试验/NCT06112769
NCT06112769已完成不适用

A Correlation Study of Internal Jugular Vein Variability Under Deep Inhalation and Propofol-induced Hypotension

Affiliated Hospital of Jiaxing University1 个研究点 分布在 1 个国家目标入组 64 人开始时间: 2023年10月29日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
64
试验地点
1
主要终点
IJVV during deep inhalation

研究概览

简要总结

The correlation between internal jugular vein variability during deep inhalation and the decrease in blood pressure during propofol induction.

详细描述

  1. Ultrasound records at least one quiet breathing cycle and one deep inhalation cycle to calculate IJVV
  2. Propofol was infused target-controlled at 4 μg/ml, and changes in arterial blood pressure within 3 minutes of propofol induction were observed.
  3. Aim to conduct a prospective observational study to evaluate the correlation between internal jugular vein variability during deep inhalation and the decrease in blood pressure during propofol induction.

研究设计

研究类型
Observational
观察模型
Case Only
时间视角
Prospective

入排标准

年龄范围
60 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • age over 60 years
  • American Society of Anesthesiology (ASA) status Ⅱ-Ⅲ
  • Surgery with radial artery puncture
  • Propofol induction

排除标准

  • BMI≥30kg/m2
  • People with short necks;
  • Previous hypotension (systolic blood pressure <90mmHg or mean arterial pressure <65mmHg)
  • Previous poorly controlled hypertension
  • Cardiac insufficiency , EF value<50%
  • Upper limb deep vein thrombosis
  • History of radiotherapy or neck surgery
  • Inability to maintain a supine position for necessary measurements
  • Mechanical ventilation status or inability to take deep breaths patients
  • gastrointestinal surgery
  • patients allergic to propofol.

结局指标

主要结局

IJVV during deep inhalation

时间窗: 1 year

IJVV (%) = (diamax - diamin)/\[(diamax + diamin)/2\] × 100

次要结局

未报告次要终点

研究者

发起方
Affiliated Hospital of Jiaxing University
申办方类型
Other
责任方
Principal Investigator
主要研究者

Qing-he Zhou

Principal investigator

Affiliated Hospital of Jiaxing University

研究点 (1)

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