Corneal Incision Healing and Its Influencing Factors After Cataract Phacoemulsification in Diabetic Patients -- Based on Anterior Segment Optical Coherence Tomography
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 110
- 试验地点
- 1
- 主要终点
- volume of half cornea with surgical incision
研究概览
简要总结
The objective of this observational study was to understand the healing of corneal incision after cataract surgery in diabetic patients and its influencing factors. The main questions it aims to answer are:
Is corneal incision healing worse in diabetic patients after cataract surgery than in non-diabetic patients? What are the factors affecting corneal incision healing after cataract surgery in diabetic patients?
The results of anterior segment optical coherence tomography before and after cataract surgery in cataract patients with or without diabetes will be collected and analyzed.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients who experience blurred vision and painless visual acuity decline, and are diagnosed with cataract (with or without diabetes) through reliable intraocular pressure, visual acuity and slit lamp examinations, and for whom phacoemulsification of cataract can be considered.
排除标准
- •Use multiple eye drops before surgery.
- •Complicated by other eye diseases that affect corneal healing, such as keratitis, uveitis, glaucoma, etc.
- •Moderate to severe dry eye.
- •History of eye surgery.
- •Moderate to severe dry eye.
- •Grade 5 nuclear cataract.
- •Severe systemic diseases (such as chronic renal failure requiring dialysis, severe neurological diseases, immune diseases), pregnancy or lactation.
结局指标
主要结局
volume of half cornea with surgical incision
时间窗: Before surgery; 1 week after surgery; 1 month after surgery
Defect of corneal incision healing
时间窗: 1 week after surgery; 1 month after surgery
Opening of internal orifice; Endothelial dislocation; Descemet's membrane detachment
次要结局
未报告次要终点