NCT06342570招募中不适用
Quantitative Analysis of EEG Changes in Response to Nociception
适应症
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 109
- 试验地点
- 1
- 主要终点
- Correlation between changes in ANI and EEG band power in response to surgical stimulation.
研究概览
简要总结
This study will quantify the nociception using Analgesia Nociception Index (ANI) during general anesthesia and analyze the differences in EEG depending on the degree of nociception. Additionally, the investigators will quantify the nociception during recovery and analyze the differences in EEG depending on the degree of nociception.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 19 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients aged ≥ 19 undergoing laparoscopic surgery
排除标准
- •Patients with arrhythmia
- •Patients with pacemaker implantation
- •Patients who have received a heart transplant
- •Patients taking medications that may affect ANI (antimuscarinics, alpha-agonist, beta blockers, etc.)
- •Patients with central nervous system disease (dementia, stroke, epilepsy, brain tumor, psychiatric disease, etc.)
- •Patients who cannot understand the consent form
结局指标
主要结局
Correlation between changes in ANI and EEG band power in response to surgical stimulation.
时间窗: When the laparoscope is inserted
Correlation between changes in ANI and EEG band power in response to surgical stimulation
次要结局
- Correlation between changes in ANI, EEG connectivity and NRS in response to analgesic administration(When analgesic drug is administered in the PACU.)
- Correlation between changes in ANI and EEG band power in response to tracheal intubation(When the tracheal intubation is conducted)
- Correlation between changes in ANI and EEG connectivity in response to surgical stimulation(When the laparoscope is inserted)
- Correlation between changes in ANI and EEG connectivity in response to tracheal intubation(When the tracheal intubation is conducted)
- Correlation between changes in ANI, EEG band power and NRS in response to analgesic administration(When analgesic drug is administered in the PACU.)
- Differences in EEG connectivity during recovery between groups with large and small changes in ANI(From admission to the PACU to discharge from the PACU)
- Differences in EEG band power(Delta, Theta, Alpha, Beta, Gamma) during surgery between groups with large and small changes in ANI(From the beginning of surgery to the end of surgery)
- Differences in EEG band power(Delta, Theta, Alpha, Beta, Gamma) during recovery between groups with large and small changes in ANI(From admission to the PACU to discharge from the PACU)
- Differences in EEG band power(Delta, Theta, Alpha, Beta, Gamma) depending on the type of inhaled anesthetic(From the beginning of surgery to the end of surgery)
- Differences in EEG connectivity during surgery between groups with large and small changes in ANI(From the beginning of surgery to the end of surgery)
- Differences in EEG connectivity depending on the type of inhaled anesthetic(From the beginning of surgery to the end of surgery)
- Differences in ANI depending on the type of inhaled anesthetic(From the beginning of surgery to the end of surgery)
研究者
Dong Woo Han
Professor
Gangnam Severance Hospital
研究点 (1)
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