A randomized study to assess the effect of high-calorie, high-carbohydrate, and/or high-fat diet on biomarkers of liver injury in healthy volunteers

Pfizer (United States)0 个研究点目标入组 12 人开始时间: 2021年4月6日最近更新: 2021年4月19日

适应症

试验速览

暂无简介。

•1. Aged 18-55 years old
•2. No clinically relevant abnormalities identified by the medical screening
•3. Body mass index (BMI) of 17.5-30.5 kg/m²
•4. Total body weight >50 kg
•5. Smoked =5 cigarettes daily
•6. Free from the use of prescription or non-prescription drugs/dietary supplements for at least seven days or five half-lives prior to the first study period

•1. Women of childbearing potential
•2. History of regular alcohol consumption (>7 drinks/week [female] or >14 drinks/week [male] within six months of screening
•3. Treatment with an investigational drug within 30 days or fice half-lives of the first study period
•4. Blood pressure =140 mm Hg (systolic) or =90 mm Hg (diastolic) following at least five minutes supine rest
•5. Consumption of alcohol, caffeine, and the use of nicotine-containing products were not permitted 24-hours prior to, and during, the resident periods of the study

发起方

Pfizer (United States)