NCT03296761Unknown不适用
Endothelial Cell Specific Molecule-1 (ESM-1): a Novel Biomarker for ARDS Endothelial Injury
Jingyuan,Xu1 个研究点 分布在 1 个国家目标入组 70 人开始时间: 2017年11月1日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 70
- 试验地点
- 1
- 主要终点
- mortality
研究概览
简要总结
To observe the changes of plasma ESM-1 levels in patients with ARDS, and to explore its clinical significance.
详细描述
70 patients who diagnosed as ARDS were included in this study. Then keep blood samples from these patients in the first day, the third day and the seventh day, detect ESM-1 level in plasma by ELISA. Record Severity of illness and survival status of every patient within 28 days. Objective to evaluate the correlation between the level of ESM-1 in plasma and the prognosis of the patients.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients admitted to ICU diagnosed of ARDS (Berlin definition）in 48h
- •Patients age between 18 years old and 80 years.
- •Exclusion Criteria：
- •Pregnant women,
- •Patients with malignant tumor,
- •Immunosuppression or immunocompromised patients.
排除标准
- 未提供
结局指标
主要结局
mortality
时间窗: 28-day
次要结局
未报告次要终点
研究者
Jingyuan,Xu
chief doctor
Southeast University, China
研究点 (1)
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