NCT04438798Unknown不适用
A Prospective Randomized Study of High Flow Nasal Cannula to Prevent Deoxygenation During Induction of General Anesthesia in Cesarean Section
适应症
试验速览
- 阶段
- 不适用
- 入组人数
- 80
- 试验地点
- 2
- 主要终点
- measure the time of safe apnea
研究概览
简要总结
Transnasal humidified rapid-insufflation ventilatory exchange (THRIVE) using high flow oxygen therapy for preoxygenation and oxygen supplementation during apnoea has shown promising results
详细描述
Eeffective preoxygenation followed by apnoeic oxygenation enables anaesthesiologists to safely prolong the apnoea time which is the time (seconds) of apnea following preoxygenation and muscle relaxation before to peripheral oxygen saturations (SpO2) decreases by 2%.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Diagnostic
- 盲法
- Single (Participant)
入排标准
- 年龄范围
- 20 Years 至 40 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •pregnant females
- •Of American Society of Anesthesiologists (ASA) physical Status I and II
- •For elective cesarean section under general anesthesia
排除标准
- •with room air saturation of <98%
- •anticipated difficult airway
- •anticipated obstetric risk factor or precious baby
- •chronic obstructive pulmonary disease
- •thyrotoxicosis
- •pheochromocytoma
- •hyperkalaemia
- •significant cardiac illness
结局指标
主要结局
measure the time of safe apnea
时间窗: 10 minutes after induction
The apnea time will start from the onset of cessation of breathing as evidenced by a flat line in the capnogram with the absence of chest movements
次要结局
未报告次要终点
研究者
rehab zayed
Assisstant Professor of Anesthesia
Alexandria University
研究点 (2)
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