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临床试验/NCT03983902
NCT03983902Unknown不适用

The Effect of Placental Transfusion Methods on the Potentially Transfusion Levels of Endothelial Progenitor Cell and CD34+ Hematopoietic Stem Cell

Ankara University0 个研究点目标入组 96 人开始时间: 2019年7月1日最近更新:
适应症

试验速览

阶段
不适用
入组人数
96
主要终点
The levels of stem cells

研究概览

简要总结

To measure the levels of endothelial progenitor cells and CD34+ hematopoietic stem cells levels, and placental residual volume by delayed cord clamping, umbilical cord milking or immediate cord clamping in newborns at different gestational weeks.

详细描述

Umbilical cord blood is a rich source of stem cells. Placental transfusion is the transfer of the placental blood to the baby until the cord clamped during the birth. Placental transfusion can be accomplished by delayed cord clamping or umbilical cord milking.

One group will receive 2 minutes of delayed cord clamping, the second group will receive umbilical cord milking and the third group will receive immediate cord clamping. Following the cord clamping, the blood samples will be taken from the placental site of the umbilical cord to measure the stem cells from all subjects and placental residual volume will be measured.

Delivery room conditions, hospitalization (if needed), short-term outcome during hospitalization, prematurity related morbidities (if baby is preterm) will be recorded.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Prevention
盲法
None

入排标准

年龄范围
— 至 3 Minutes(Child)
性别
All
接受健康志愿者

入选标准

  • Born at 24 weeks to 42 weeks infants

排除标准

  • Without parental consent, known congenital anomalies

结局指标

主要结局

The levels of stem cells

时间窗: 18-months

Measurement of the levels of endothelial progenitor cells and CD34+ hematopoietic stem cells

次要结局

  • Placental residual volume(18-months)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Emel Okulu,MD

Principal Investigator

Ankara University

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