Assessing the Relation Between Subcortical LFPs and DBS Parameter Selection in Parkinson's Disease - a Prospective Study
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 40
- 试验地点
- 1
- 主要终点
- Alignment of contact selection
研究概览
简要总结
The goal of this observational study is to assess whether deep brain stimulation (DBS) contact selection in Parkinson's disease could be informed by subcortical local field potential (LFP) recordings. The main question it aims to answer is:
Aligns stimulation contact selection based on subcortical LFP recordings with clinically optimized contact selection?
Participants will undergo LFP recordings that are part of standard clinical care during their routine hospital visits.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Voluntary written informed consent of the participant
- •At least 18 years of age at the time of signing the Informed Consent Form (ICF)
- •Diagnosis of idiopathic Parkinson's disease according to the clinical diagnostic criteria of the Movement Disorder Society (MDS)
- •Eligible for DBS to treat refractory PD motor symptoms, as based on multidisciplinary DBS screening
- •Have sufficient understanding of the Dutch and French language to participate in the study
排除标准
- 未提供
结局指标
主要结局
Alignment of contact selection
时间窗: From the first LFP recording to the last LFP recording (6 - 9 months)
Alignment between local field potential-based contact selection and the clinically optimized stimulation contact.
次要结局
未报告次要终点
研究者
Loes Laurijssen
MD
University Hospital of Leuven Leuven