Effects of timing of food intake on glucose metabolism and the brain during a hypocaloric diet in obese subjects - TIME-study

Academisch Medisch Centrum0 个研究点目标入组 25 人开始时间: 待定最近更新: 2024年4月23日

适应症

试验速览

暂无简介。

•- BMI * 30kg/m2
•- Age 50-80 years
•- At least 3 out of 5 metabolic syndrome criteria: fasting plasma glucose * 5.6 mmol/l, triglycerides * 1.7 mmol/l, waist-circumference > 102 cm, HDL-cholesterol 1.04 mmol/l, blood pressure * 130/85 mmHg
•- Stable weight three months prior to study inclusion

•- Use of any medication except for those related to treatment of components of the metabolic syndrome (excluding insulin, oral glucose lowering drugs, beta-blockers)
•- Any actual medical condition except for treated hypothyroidism and the metabolic syndrome
•- History of any psychiatric disorder
•- Shift work
•- Irregular sleep pattern
•- Intensive sports (>3/week)
•- Restrained eaters
•- History of eating disorders (anorexia, binge eating, bulimia)
•- Smoking, XTC, amphetamine or cocaine abuse
•- Alcohol abuse (>3/day)
•- Contraindication MRI
•- Lactose intolerance

发起方