Traveling Wave Transcranial Alternating Current Stimulation for the Control of Large-Scale Brain Networks
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 9
- 试验地点
- 2
- 主要终点
- Electrophysiological outcomes
研究概览
简要总结
This project will assess the feasibility of traveling wave transcranial alternating current stimulation (tACS) to modify working memory performance and large-scale brain connectivity in surgical epilepsy patients.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Basic Science
- 盲法
- Single (Participant)
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •the patient can consent for themselves;
- •the patient has or is scheduled for surgically implanted electrodes for the purposes of phase II epilepsy surgical evaluation;
- •age 18+ years old;
排除标准
- •1. diminished capacity to consent;
研究组 & 干预措施
Stimulation Theta Group
Participants will experience traveling wave transcranial alternating current stimulation over the fronto-parietal regions at 4 Hz (theta condition).
干预措施: Transcranial alternating current stimulation (Device)
Stimulation Beta Group
Participants will experience traveling wave transcranial alternating current stimulation over the fronto-parietal regions at 23 Hz (beta condition).
干预措施: Transcranial alternating current stimulation (Device)
结局指标
主要结局
Electrophysiological outcomes
时间窗: Immediate effect during stimulation
Changes in spectral power and coherence of the local field potentials during transcranial electric stimulation relative to no stimulation periods.
Working memory outcomes
时间窗: Immediate effect during stimulation
Changes in working memory performance as measured with the N-back task (quantified with d-prime) during stimulation.
次要结局
未报告次要终点