Nalbuphine as an Adjuvant to Levobupivacaine in Caudal Analgesia in Children
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 64
- 试验地点
- 1
- 主要终点
- duration of analgesia
研究概览
简要总结
Caudal anesthesia is the single most important pediatric regional anesthetic technique and is increasingly performed in pediatric regional anesthesia practices. It is preferred in order to relieve intra-operative and postoperative pain in children of all age groups undergoing pelvi-abdominal or lower limbs surgeries using levobupivacaine 0.25%.Various adjuvants have been added to levobupivacaine to prolong postoperative caudal analgesia. Nalbuphine as many opioids can be added in caudal analgesia. This prospective randomized double blind study was done to compare the effects of plain levobupivacaine versus Levobupivacaine plus nalbuphine single-shot for postoperative pain relief in children undergoing hypospadius repair surgery.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Supportive Care
- 盲法
- None
入排标准
- 年龄范围
- 1 Year 至 3 Years（Child）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •ASA I, II.
- •Age 1-3 years.
- •Patients scheduled for hypospadias repair surgeries.
排除标准
- •ASA III, IV.
- •Signs of infection at site of injection.
- •Known coagulopathy disorder.
- •Mental and / or developmental retardation.
结局指标
主要结局
duration of analgesia
时间窗: 24hours
Time to first analgesia request (TFAR)
Quality of Postoperative analgesia
时间窗: 24 hours
Face legs activity cry consolablity score (FLACC) (0-10) Score: 0, no pain; 1-3, mild pain; 4-7, moderate pain; 8-10, severe pain
次要结局
- analgesic consumption(24 hours)