Cardiac 4D MR Velocity Mapping in Repaired Tetralogy of Fallot Patients: Evaluation of Pulmonary Regurgitant Fraction and Ventricular Volume
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 21
- 试验地点
- 2
- 主要终点
- Regurgitant fraction comparison
研究概览
简要总结
MRI with 4D flow permits to assess the hemodynamic parameters in a parent vessel and its branches inside the same sequence.
详细描述
MRI with 4D flow permits to assess the hemodynamic parameters in a parent vessel and its branches inside the same sequence. The objective of the project is to compare the regurgitant fraction in the pulmonary artery (PA) measured using 4D MR-flow and standard 2D MR-flow in repaired Tetralogy of Fallot (rTOF) patients. The consistency of the 4D flow quantization will be assessed assuming mass conservation in the pulmonary artery tree (PA flow =LeftPA flow +RightPA flow ? ).
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Basic Science
- 盲法
- None
入排标准
- 年龄范围
- 15 Years 至 —（Child, Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Tetralogy of Fallot patients
- •referred for clinical MRI examination
- •≥ 15 years
排除标准
- •Anyone with a classic contraindication to MRI
- •Severe obesity
- •Gadolinium chelate allergy
- •< 15 years
- •counter-indication to MRI examination
- •vulnerable person
研究组 & 干预措施
Participants to 4D flow imaging
In addition to the standard clinical MR protocol, 2 added sequences:
4D MR sequence in cine mode 4D velocity mapping sequence
干预措施: 4D flow imaging (Device)
结局指标
主要结局
Regurgitant fraction comparison
时间窗: Day 0
The primary objective of the project is to compare the regurgitant fraction in the pulmonary artery (PA) measured with 4D MR-flow and standard 2D MR-flow.
次要结局
- Pulmonary arteries flows(Day 0)
- Right ventricular volume(Day 0)