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临床试验/NCT04100304
NCT04100304Unknown不适用

Preoperative Evaluation of the Remaining Part of the Liver for Liver Resection

Assiut University0 个研究点目标入组 30 人开始时间: 2019年10月1日最近更新:
适应症
干预措施

试验速览

阶段
不适用
入组人数
30
主要终点
Evaluation

研究概览

简要总结

  • Review the outcomes of the current treatments modalities.
  • Give an effective treatment .
  • Improve the outcome of these patients and decease rate of recurrence and complications.
  • An adequate future liver remnant (FLR) reduces the risk of postoperative liver failure after major hepatectomy.
  • incurs a risk of postoperative liver dysfunction and infection and there is a lack of objective evidence relating residual liver volume to these complications

详细描述

A liver resection is the surgical removal of all or a portion of the liver. It is also referred to as a hepatectomy, full or partial. A complete liver resection is performed in the setting of a transplant a diseased liver is removed from a deceased donor (cadaver). A living donor may also provide a piece of liver tissue which is procured through a partial hepatectomy, The procedure may be performed through a traditional open procedure or using minimally invasive techniques.

When is Liver Resection Performed Most hepatectomies are performed for the treatment of hepatic neoplasms, both benign or malignant. Benign neoplasms include hepatocellular adenoma, hepatic hemangioma and focal nodular hyperplasia.The most common malignant neoplasms (cancers) of the liver are metastases; those arising from colorectal cancer are among the most common, and the most amenable to surgical resection. The most common primary malignant tumour of the liver is the hepatocellular carcinoma. Hepatectomy may also be the procedure of choice to treat intrahepatic gallstones or parasitic cysts of the liver.

Liver surgery is safe when performed by experienced surgeons with appropriate technological and institutional support. As with most major surgical procedures, there is a marked tendency towards optimal results at the hands of surgeons with high caseloads in selected centres (typically cancer academic medical centers and transplantation centers).

Partial hepatectomy is surgery to remove part of the liver. Only people with good liver function who are healthy enough for surgery and who have a single tumor that has not grown into blood vessels can have this operation.

Imaging tests, such as CT or MRI with angiography are done first to see if the cancer can be removed completely. Still, sometimes during surgery the cancer is found to be too large or has spread too far to be removed, and the surgery that has been planned cannot be done.

研究设计

研究类型
Interventional
分配方式
Na
干预模型
Single Group
主要目的
Treatment
盲法
None

入排标准

性别
All
接受健康志愿者

入选标准

  • Patients undergoing liver resection for benign or malignant hepatic neoplasm at the time of study(two years)
  • Patient consent.
  • Age of the patient : Any age

排除标准

  • patients has contraindication to do liver resection surgery.
  • patients who are unfit for any surgical interventions.
  • patients who refuse the operation or refusing to share his data.

研究组 & 干预措施

patient under going liver resection

Other

干预措施: resection (Diagnostic Test)

结局指标

主要结局

Evaluation

时间窗: preoperative

Evaluation of the remaining part of the liver by CTvolumetry for further management as liver transplant

次要结局

  • energy expenditure([ Time Frame: 30 days ])
  • Procedural parameters(intraoperative)
  • Long-term outcomes(5 years)
  • Perioperative liver function(30 days preoperative)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Moaz Ahmed Sayed Ahmed

resident doctor at general surgery department

Assiut University

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