Study for the intestinal microflora remodeling and microRNA regulation mechanism of acupuncture in patients with functional constipation

Chengdu University of Traditional Chinese Medicine0 个研究点开始时间: 待定最近更新: 2023年2月20日

适应症

试验速览

暂无简介。

•1. Men or women aged 18-60 years;
•2. According with Rome IV diagnostic criteria for functional constipation, with a history of constipation of at least half a year;
•3. Severe constipation, complete spontaneous defecation <= 2 times a week, and has lasted for more than 3 months;
•4. The patients had no special eating habits, anxiety, depression and other mental disorders;
•5. At baseline, the patients had difficulty in defecation and dry stool (BSFS <= 3); Did not take any medicine for constipation, including intestinal microecology, probiotics, etc;
•6. Did not receive acupuncture treatment for constipation in the past three months and lived in Chengdu or surrounding areas for a long time.

•1. History of abdominal or anorectal surgery;
•2. Irritable bowel syndrome and organic or drug-induced constipation; Secondary to endocrine, metabolic or neurogenic constipation;
•3. Patients with heart, liver, kidney damage or cognitive impairment, aphasia, or unable to cooperate with sample collection and treatment;
•4. Pregnancy, lactation, postpartum and allergic constitution;
•5. Coagulation dysfunction or anticoagulants such as farwarfarin and heparin have been used.

发起方

Chengdu University of Traditional Chinese Medicine