Circulatory Levels of Irisin in Response to Chronic Resistance Training
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 28
- 试验地点
- 1
- 主要终点
- Blood Lactate levels
研究概览
简要总结
Study the responses of circulatory irisin to chronic high-intensity resistance training
详细描述
Objective: The purpose of this study is to study the circulating levels of irisin in response to chronic high-intensity resistance training in a group of healthy young adults.
Sample: The sample will be comprised 44 of adult men and women unpaid volunteers between the ages of 18 and 30.
Pre-screening assessments:
Informed consent, PAR-Q, Medical History and Exercise History will be used to determine health status and prior exercise experience. Menstrual cycle log will be required for female participants.
Pre-Intervention assessments:
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Basic Science
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 30 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Exclusion Criteria:
- •Known health problems such as cardiovascular, pulmonary or metabolic disease will be excluded.
- •Pregnant females.
- •Any adults found taking medications that affect endocrine or cardiovascular function will also be excluded from the study.
- •Individuals found to be less than 110 pounds.
- •Participants that exercise more than three times per week or strength train more than twice per week.
- •Individuals that have poor venous access or have expressed a fear of needles or having blood taken will also be excluded.
- •Cigarette smoking (current or those who quit within the previous 6 months
- •Hypertension
- •Overweight and obese
- •Pre-diabetics
排除标准
- •Known health problems such as cardiovascular, pulmonary or metabolic disease will be excluded.
- •Pregnant females.
- •Any adults found taking medications that affect endocrine or cardiovascular function will also be excluded from the study.
- •Individuals found to be less than 110 pounds.
- •Participants that exercise more than three times per week or strength train more than twice per week.
- •Individuals that have poor venous access or have expressed a fear of needles or having blood taken will also be excluded.
- •Cigarette smoking (current or those who quit within the previous 6 months
- •Hypertension
- •Overweight and obese
- •Pre-diabetics
研究组 & 干预措施
Intervention
The acute intervention will consist of 1 session of training following the program:
Resistance Training Exercises. Each participant in the intervention group will perform resistance-training exercises in the form of a circuit. The circuit will consist of 10 repetitions per exercise of 7 exercises: leg press, bent-over row, bench press, squats, dumbbell jump squats with raises, dead-lifts and weighted abdominal crunches, with approximately 30 sec of rest in between each exercise (based on the estimated time needed to move from one position to the next). Initial intensity 6-7 of RPE and ending the set at 9-10. Each participant will move through the circuit 3 times, with 2 to 3 minutes of rest between each round.
干预措施: Exercise Training (Other)
Control
Control
结局指标
主要结局
Blood Lactate levels
时间窗: 3 weeks
Intensity of exercise on sessions 1, 3, 6 and 9
Changes in Hematocrit concentration
时间窗: Baseline and 3 weeks
Changes in physical fitness levels as meassured by 1RM (repetition maximum) and Cardio-respiratory maximal testing
时间窗: Baseline and 3 weeks
Physical Activity assessment: accelerometry
时间窗: 3 weeks
Changes in Body composition assessment: DEXA and anthropometry
时间窗: Baseline and 3 weeks
Changes in Blood glucose levels
时间窗: Baseline and 3 weeks
Diet assessment: 24 hour recall and Food Preference Questionnaire
时间窗: 3 weeks
Change in Serum irisin levels
时间窗: Baseline and 3 weeks
次要结局
未报告次要终点