Short term evaluation of the ocular response to caffeine eye-drops and caffeine plus atropine eye-drops in healthy volunteers..

Brien Holden Vision Insitute0 个研究点目标入组 20 人开始时间: 2018年2月7日最近更新: 2019年7月15日

适应症

试验速览

暂无简介。

•Able to read and comprehend English and give informed consent as demonstrated by signing a record of informed consent.
•Be at least 18 years old, male or female.
•Willing to instil each of the test eye drops daily for 5 days and follow the clinical trial visit schedule as directed by the Investigator.
•Have ocular health findings considered to be normal”.

•Any pre-existing ocular irritation, injury or condition, including infection or disease.
•Any systemic disease that adversely affects ocular health e.g. diabetes, Graves disease, and auto-immune diseases such as ankylosing spondylitis, multiple sclerosis, Sjögrens syndrome and systemic lupus erythematosus. Conditions such as systemic hypertension and arthritis do not automatically exclude prospective participants.
•Use of or a need for concurrent category S3 and above ocular medication at enrolment and/or during the clinical trial.
•Use of or a need for any systemic medication or topical medications which may alter normal ocular findings / are known to affect a participant’s ocular health / physiology or contact lens performance either in an adverse or beneficial manner at enrolment and/or during the clinical trial.
•Eye surgery within 12 weeks immediately prior to enrolment for this trial.
•Previous corneal refractive surgery.
•Contraindications to caffeine such as high blood pressure, heart conditions and ADHD
•Known allergy or intolerance to ingredients to caffeine.
•Contact lens wearer
•Pregnancy and breastfeeding.*
•Currently enrolled in another clinical trial.
•The Investigator may, at his/her discretion, exclude anyone who they believe may not be able to fulfil the clinical trial requirements or it is believed to be in the participant’s best interests.
•*Formal testing of pregnancy is not required. A participant’s verbal report is sufficient.

发起方

Brien Holden Vision Insitute