NCT01128790已完成不适用
Effect of Remote Ischemic Preconditioning on Exercise Capacity in Patients With Heart Failure: A Double Blind Randomized Control Trial
适应症
干预措施
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 22
- 试验地点
- 1
- 主要终点
- Exercise performance - VO2, exercise time, exercise workload, anaerobic threshold
研究概览
简要总结
The purpose of this study is to determine the effect of remote ischemic preconditioning on exercise capacity in patients with heart failure.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Treatment
- 盲法
- Triple (Participant, Care Provider, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •LV ejection fraction <40%
- •NYHA functional class II-IV
- •Non ischemic cardiomyopathy
排除标准
- •recent cardiovascular hospitalization (within last 4 weeks)
- •ischemic cardiomyopathy
- •diabetes mellitus
- •peripheral neuropathy
- •ventricular assist device
- •contraindications to exercise stress testing
研究组 & 干预措施
remote ischemic preconditioning
Experimental
4 cycles of 5 mins upper limb ischemia induced by blood pressure cuff inflation 20mmHg above systolic blood pressure
干预措施: Remote ischemic preconditioning (Other)
Sham control
Sham Comparator
4 x 5 mins of upper limb blood pressure cuff inflation to 10mmHg (non-occlusive)
干预措施: Sham Control (Other)
结局指标
主要结局
Exercise performance - VO2, exercise time, exercise workload, anaerobic threshold
时间窗: 1 week
次要结局
未报告次要终点
研究者
研究点 (1)
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