Fibrin Glue Versus Titanium Platelet-rich Fibrin as a Sole Filling Material in Lateral Sinus Lifting With Simultaneous Implant Placement (Randomized Controlled Clinical Trial )
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 30
- 试验地点
- 2
- 主要终点
- change in bone density
研究概览
简要总结
Graftless sinus lift with simultaneous implant placement is one of the new techniques, this new technique is presented based on the physiology of intrasinus bone repair.
Schneiderian membrane is known to have an osteogenic nature, now blood clot can be considered autologous osteogenic graft material, to which osteoprogenitors can migrate, differentiate, and regenerate bone.
The aim of this study is to evaluate the effectiveness of using Fibrin glue versus Titanium platelet rich fibrin (T-PRF) as a sole filling material in lateral sinus lifting using with simultaneous implant placement in comparison to a negative control group.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 20 Years 至 60 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients requiring implant placement in the posterior maxilla.
- •Tooth extractions at the implant sites were performed at least 4 months before surgery.
- •Residual bone height between the alveolar bone crest and the sinus floor is 3-5 mm
排除标准
- •Maxillary sinus pathologies (sinusitis, long-standing nasal obstruction).
- •Any disease-contraindicating surgery (e.g. uncontrolled diabetes).
- •Heavy smokers (smoke greater than or equal 25 cigarettes daily).
- •Acute oral infections.
- •Untreated periodontal disease (gingival index 2 and 3).
- •Poor oral hygiene ( Silness-Löe index (score 2-3) ).
- •A history of radiotherapy or chemotherapy of the head and neck region.
- •Pregnancy.
结局指标
主要结局
change in bone density
时间窗: Baseline and 6 months
bone density will be measured using CBCT
change in implant stability
时间窗: Baseline and 6 months
implant stability will be measures using Ostell device.
change in vertical bone height
时间窗: Baseline and 6 months
vertical bone height will be measured using CBCT
次要结局
- change in pain intensity(Through 1 week postopertaive)
- Change in edema score(Through 1 week postopertaive)
研究者
Hams Hamed Abdelrahman
Assistant lecturer of DPH and Clinical statistician
Alexandria University