NCT00291395终止1 期
PGI2 Induced Headache and Cerebral Haemodynamics in Healthy Volunteers
适应症
相关药物
试验速览
- 阶段
- 1 期
- 状态
- 终止
- 入组人数
- 12
- 试验地点
- 2
- 主要终点
- Headache
研究概览
简要总结
Before , during and after intravenous administration of PGI2 we score/measure headache, rCBF, blood flow in middle cerebral artery and diameter of superficial temporal artery/radial artery and correlate that to known patophysiology of headache to see if PGI2 is involved in headache pathophysiology.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 盲法
- Double
入排标准
- 年龄范围
- 18 Years 至 40 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Healthy volunteers,
排除标准
- •Primary headache,
- •headache on the day of investigation,
- •Hypertension,
- •hypotension,
- •pregnant/nursing
- •Daily intake of medication (except oral contraceptives)
- •Cardiovascular or CNS disease
- •Drug/Alcohol abuse
- •Psychiatric disease
结局指标
主要结局
Headache
次要结局
- rCBF, blood flow, diameter of STA/RA, HR, BP
研究者
研究点 (2)
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