Multimodal Postoperative Analgesia Using Accufuser for Multilevel Surgery for Obstructive Sleep Apnea (OSA)
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 30
- 试验地点
- 1
- 主要终点
- Postoperative pain
研究概览
简要总结
Assessment of the clinical efficacy and adverse effects of multimodal analgesic regimen consisting of nalbuphine combined with ketorolac using IV continuous infusion silicon device (Accufuser) for postoperative analgesia following multilevel OSA surgeries
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 30 Years 至 50 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •physical status of American Society of Anesthesiologists (ASA) II
- •age between 30 - 50 years
- •OSA patients diagnosed by polysomnography and stop-bang questionnaire
- •enrolled for multilevel OSA surgery
排除标准
- •history of allergy to the study drugs
- •history of hepatic, cardiopulmonary or renal disease
- •history of any chronic pain on medication
- •history of substance abuse
- •psychiatric disorder
- •lack of patient cooperation.
研究组 & 干预措施
OSA patients after multilevel surgery
干预措施: Nalbuphine, ketorolac, accufuser (Combination Product)
结局指标
主要结局
Postoperative pain
时间窗: Assessment will be carried out 48 hours postoperatively
Visual analog pain score
Postoperative pain
时间窗: Assessment will be carried out at zero time (time to shift to PACU) .
visual analog pain score
Postoperative pain
时间窗: Assessment will be carried out 6 hours postoperatively
Visual analog pain score
Postoperative pain
时间窗: Assessment will be carried out 12 hours postoperatively
Visual analog pain score
Postoperative pain
时间窗: Assessment will be carried out 18 hours postoperatively
Visual analog pain score
Postoperative pain
时间窗: Assessment will be carried out 24 hours postoperatively
Visual analog pain score
Postoperative pain
时间窗: Assessment will be carried out 30 hours postoperatively
Visual analog pain score
Postoperative pain
时间窗: Assessment will be carried out 36 hours postoperatively
Visual analog pain score
Postoperative pain
时间窗: Assessment will be carried out 42 hours postoperatively
Visual analog pain score
次要结局
- Sedation level(48 hours postoperatively)
- incidence of adverse effects(48 hours postoperatively)
- Sedation level(12 hours postoperatively)
- Sedation level(18 hours postoperatively)
- Sedation level(24 hours postoperatively)
- Sedation level(30 hours postoperatively)
- Sedation level(Zero time ( time to shift to PACU))
- Sedation level(6 hours postoperatively)
- Sedation level(36 hours postoperatively)
- Sedation level(42 hours postoperatively)
- incidence of adverse effects(Zero time ( time to shift to PACU))
- incidence of adverse effects(6 hours postoperatively)
- incidence of adverse effects(12 hours postoperatively)
- incidence of adverse effects(18 hours postoperatively)
- incidence of adverse effects(24 hours postoperatively)
- incidence of adverse effects(30 hours postoperatively)
- incidence of adverse effects(36 hours postoperatively)
- incidence of adverse effects(42 hours postoperatively)
研究者
Bahaa Mohammed Refaie
Lecturer of anesthesia and ICU
Sohag University