The role of FTO Gene Variants on Metabolic Flexibility and Training Adaptations in Relatively Healthy Males following a 12 Week High Intensity Exercise Intervention

Victoria University0 个研究点目标入组 20 人开始时间: 2013年1月16日最近更新: 2020年1月13日

适应症

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•Participants will be considered relatively healthy males with the FTO rs9939609 risk allele (A) or two FTO rs9939609 wild type alleles (TT). Participants will be included if they have adequate glucose handling (no diagnosed diabetes, fasting blood glucose must be less than 7.0 mmol/L), not performing any regular fitness training (i.e. greater than 30 minutes, 3 times per week) for the past 6 months, not taking contraindicated prescription medication (i.e. thyroid, hyperlipidmeic, hypoglycemic, or antihypertensive), do have physician approval (if BMI over 25kg.m-2), and not current involvement in other research studies.

•Participants will be excluded from participating within the project for the following reasons: diagnosed diabetes (fasting blood glucose greater than 7.0 mmol/L or HbA1ctest greater than 6.5%), performing any regular fitness training (i.e. greater than 30 minutes, 3 times per week) for the past 6 months, taking contraindicated prescription medication (i.e. thyroid, hyperlipidmeic, hypoglycemic, or antihypertensive), no physician approval (if BMI over 25kg.m-2), and current involvement in other research studies.

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