NCT01845753已完成不适用
Molecular Screening for Lynch Syndrome in Denmark
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 5,000
- 试验地点
- 3
- 主要终点
- Rate of Lynch Syndrome in a population of primary colorectal cancer
研究概览
简要总结
A clinically applicably strategy for molecular screening for Lynch Syndrome is being implemented in Denmark.
Based on sequential analysis with immunohistochemistry and methylation analysis, patients with possible hereditary colorectal cancer are identified. These patients are offered genetic risk assessment and counselling.
The study hypothesis is that molecular screening will identify more patients with Lynch Syndrome than the family history alone.
Prospective data collection is performed using established clinical databases.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Histological diagnosis of colorectal adenocarcinoma
- •Diagnosed at one of the departments of pathology in Denmark
排除标准
- 未提供
结局指标
主要结局
Rate of Lynch Syndrome in a population of primary colorectal cancer
时间窗: 1 year
次要结局
未报告次要终点
研究者
研究点 (3)
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