Assessment of Preload Dependency Via Measurement of Peripheral Venous Pressure During an Alveolar Recruitment Manoeuvre
试验速览
- 阶段
- 不适用
- 状态
- 终止
- 发起方
- 入组人数
- 21
- 试验地点
- 2
- 主要终点
- Primary outcome measure
研究概览
简要总结
Assessment of preload dependency via measurement of peripheral venous pressure during an alveolar recruitment manoeuvre.
Prospective multicentre open-label study of mechanically ventilated intensive care patients.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Prevention
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients aged 18 years or older, for whom the trusted person designated by the patient or, failing that, a relative has read and signed the consent form for participation in the study
- •Patient hospitalised in intensive care, under sedation and controlled mechanical ventilation
- •Equipped with a central venous line in the superior vena cava territory and an arterial catheter.
- •Whose state of health justifies vascular filling
排除标准
- •Patient under legal protection, guardianship or curatorship
- •Pregnant or breastfeeding woman
- •Patient not affiliated to the French social security system
- •Contraindication to the realization of an alveolar recruitment maneuver
结局指标
主要结局
Primary outcome measure
时间窗: through study completion, an average of 12 hours
The correlation between the pairs of values of CVP and PVP during an alveolar recruitment manoeuvre will be evaluated by Pearson's coefficient or Spearman's coefficient if the distribution of the values is not parametric. The coefficient of determination r² will be calculated by linear regression between the 2 variables. Finally, the agreement between the two measurements will be evaluated by the Bland-Altman method: the Bland-Altman graph will be provided and the 95% agreement limits will be calculated (+/- 1.96 SD, SD being the standard deviation of the difference between the measurements).
次要结局
- Secondary outcome measure(through study completion, an average of 12 hours)