NCT02132871已完成不适用
Noninvasive Assessment of Preload Dependency by Passive Leg Raising Test and Impedance Cardiography Compared to Echocardiographic Measurements After Cardiac Surgery
University Hospital, Strasbourg, France1 个研究点 分布在 1 个国家目标入组 65 人开始时间: 2014年5月最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 65
- 试验地点
- 1
- 主要终点
- Area under ROC curve comparing SV variation (impedance cardiography) and VTI variation after PLR
研究概览
简要总结
The primary purpose of this study is to investigate wether the measure of stroke volume (SV) variations by impedance cardiography during passive leg raising (PLR) can reliably predict preload dependency after cardiac surgery, in comparison to a reference parameter : velocity time integral (VTI) variation measured by transthoracical echocardiography.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Men or women over 18 years
- •Affiliated to a social protection
- •Signed written consent
- •Informed about the results of the medical visit
- •All type of cardiac surgery with extracorporeal circulation performed at University Hospital of Strasbourg
- •Sedated and under mechanical ventilation
排除标准
- •Cardiac arrhythmia
- •Contraindication to PLR maneuver
- •Exclusion period due to inclusion in a previous or ongoing study
- •Impossibility to provide enlightened information
- •Patient deprived of liberty, under judicial protection, trusteeship or guardianship
- •Pregnancy, lactation
结局指标
主要结局
Area under ROC curve comparing SV variation (impedance cardiography) and VTI variation after PLR
时间窗: Within the 6 first hours after cardiac surgery
Patients classified as responders and non responders to PLR : VTI variation ≥ 12% or \< 12%
次要结局
- Variation of central veinous pressure, left auricular pressure and left ventricular filling pressures after PLR (ROC curves, correlation tests)(Within the 6 first hours after cardiac surgery)
- Respiratory variation of inferior vena cava(Within the 6 first hours after cardiac surgery)
研究者
研究点 (1)
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