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临床试验/ISRCTN79038750
ISRCTN79038750已完成未知

ACE inhibitors to augment the effects of pulmonary rehabilitation in COPD

Imperial College London (UK)0 个研究点目标入组 80 人开始时间: 2012年11月29日最近更新:

试验速览

阶段
未知
状态
已完成
发起方
入组人数
80

研究概览

简要总结

暂无简介。

研究设计

研究类型
Interventional

入排标准

性别
All

入选标准

  • Adults with GOLD stage II-IV COPD and a clinical indication for pulmonary rehabilitation (MRC score of 3 or more or functionally limited)

排除标准

  • 1. Clinically unstable patients (within one month of exacerbation)
  • 2. Those with a permanent pacemaker (which is a contraindication to magnetic stimulation), or significant co-morbidity
  • 3. Patients with an accepted indication for ACE inhibition (left ventricular dysfunction, diabetes) or a contraindication such as renovascular disease
  • 4. Creatinine clearance (estimated) <50)
  • 5. Hypotension
  • 6. Use of anticoagulants (contra-indication to biopsy) or ACE-I or ATII receptor antagonists
  • 7. Allergy to ACE-inhibitors
  • 8. Pregnancy

研究者

发起方
Imperial College London (UK)

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