ISRCTN79038750已完成未知
ACE inhibitors to augment the effects of pulmonary rehabilitation in COPD
Imperial College London (UK)0 个研究点目标入组 80 人开始时间: 2012年11月29日最近更新:
试验速览
- 阶段
- 未知
- 状态
- 已完成
- 发起方
- 入组人数
- 80
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 性别
- All
入选标准
- •Adults with GOLD stage II-IV COPD and a clinical indication for pulmonary rehabilitation (MRC score of 3 or more or functionally limited)
排除标准
- •1. Clinically unstable patients (within one month of exacerbation)
- •2. Those with a permanent pacemaker (which is a contraindication to magnetic stimulation), or significant co-morbidity
- •3. Patients with an accepted indication for ACE inhibition (left ventricular dysfunction, diabetes) or a contraindication such as renovascular disease
- •4. Creatinine clearance (estimated) <50)
- •5. Hypotension
- •6. Use of anticoagulants (contra-indication to biopsy) or ACE-I or ATII receptor antagonists
- •7. Allergy to ACE-inhibitors
- •8. Pregnancy
研究者
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