跳至主要内容
临床试验/EUCTR2012-000413-36-GB
EUCTR2012-000413-36-GB进行中(未招募)1 期

ACE-EPIC: ACE inhibitors to enhance the effects of pulmonary rehabilitation in COPD - ACE-EPIC: Enhancing the effects of pulmonary rehabilitation in COPD

Imperial College0 个研究点目标入组 80 人开始时间: 2012年3月28日最近更新:
适应症
相关药物

试验速览

阶段
1 期
状态
进行中(未招募)
发起方
入组人数
80

研究概览

简要总结

暂无简介。

研究设计

研究类型
Interventional clinical trial of medicinal product

入排标准

入选标准

  • GOLD stage II-IV COPD
  • Clinical indication for PR (MRC score of >3 or functionally limited)
  • Are the trial subjects under 18? no
  • Number of subjects for this age range: 0
  • F.1.2 Adults (18-64 years) yes
  • F.1.2.1 Number of subjects for this age range 40
  • F.1.3 Elderly (>=65 years) yes
  • F.1.3.1 Number of subjects for this age range 40

排除标准

  • Clinically unstable patients (within one month of exacerbation), those with a permanent pacemaker (which is a contraindication to magnetic stimulation), or significant co-morbidity, patients with an accepted indication for ACE inhibition (left ventricular dysfunction, diabetes) or a contraindication such as renovascular disease; creatinine clearance (estimated) <50); hypotension; use of anticoagulants (contra-indication to biopsy) or ACE-I or ATII receptor antagonists.
  • Allergy to ACE-inhibitors.

研究者

发起方
Imperial College

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