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临床试验/NCT03028454
NCT03028454已完成不适用

Effects of Ginger on Muscle Soreness and Dysfunction Stemming From Downhill Running

Old Dominion University1 个研究点 分布在 1 个国家目标入组 34 人开始时间: 2017年1月1日最近更新:
适应症
干预措施

试验速览

阶段
不适用
状态
已完成
入组人数
34
试验地点
1
主要终点
Muscle Soreness Change

研究概览

简要总结

The objective of the study is to determine whether five days of ginger (Zingiber officinale) supplementation is effective at reducing muscle soreness and improving muscle function following downhill running. Long-distance running is often associated with acute muscle pain, swelling, and reduced muscle functioning, and consequently, many runners utilize non-steroidal anti-inflammatory drugs (NSAID). NSAID use is associated with gastrointestinal side-effects such as stomach discomfort, nausea, dyspepsia, asymptomatic ulcers, and symptomatic ulcers that, although rare, can be fatal. Ginger is a botanical compound that is Generally Recognized as Safe by the Food and Drug Administration (FDA). Evidence from osteoarthritis, dysmenorrhea, and resistance-training models indicate that ginger is effective at reducing general pain and muscle soreness. Therefore, this study will supplement 60 runners with roughly 1.5 g/day of ginger root or a placebo for 2 days prior to, the day of, and 2 days after downhill running. Participants will be evaluated for muscle soreness and function before and after the downhill run.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Basic Science
盲法
Double (Participant, Investigator)

入排标准

年龄范围
18 Years 至 65 Years(Adult, Older Adult)
性别
All
接受健康志愿者
是

入选标准

  • •Be currently running ≥10 miles per week
  • •Have completed at least one run >40 minutes over the past month

排除标准

  • •Have no allergies to ginger
  • •Willing to avoid pain-relieving medications for the duration of the study
  • •Have no history of bleeding disorders nor currently taking blood thinners

研究组 & 干预措施

Ginger Root Capsule

Experimental

干预措施: Ginger Root (Dietary Supplement)

Placebo Capsule

Placebo Comparator

干预措施: Placebo (Dietary Supplement)

结局指标

主要结局

Muscle Soreness Change

时间窗: Two days before a 40-minute downhill run, the day of a 40-minute downhill run, 24 hours after a 40-minute downhill run and the two days after a 40-minute downhill run

Participants will be asked to mark a slash on a 100 mm line the muscle soreness of their lower extremities, with descriptors of "no soreness'' indicated at 0 and ''unbearably painful" at 100. Participants will rate overall lower-extremity soreness at rest, while performing a stand-to-sit movement, and while running at a moderate pace.

次要结局

  • Pain Pressure Threshold Change(Two days before a 40-minute downhill run, the day of a 40-minute downhill run, and two days after a 40-minute downhill run)
  • Vertical Jump Test Change(Two days before a 40-minute downhill run, the day of a 40-minute downhill run, and two days after a 40-minute downhill run)
  • 1.5-mile Run Change(Two days before a 40-minute downhill run and two days after a 40-minute downhill run)
  • Lung Function Change(Two days before a 40-minute downhill run and two days after a 40-minute downhill run)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Patrick Wilson, PhD

Assistant Professor of Exercise Science

Old Dominion University

研究点 (1)

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