Comparative evaluation of onset and recovery characteristics of minimal flow Sevoflurane and Desflurane anaesthesia
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 48
- 试验地点
- 1
- 主要终点
- 1.Onset time
研究概览
简要总结
Sevoflurane and Desflurane are the two most common gases used in minimal flow anaesthesia.
The aim of this study is to evaluate and compare the onset and recovery characteristics in minimal flow sevoflurane and desflurane anaesthesia.
Patients will be divided into two groups Group D and Group S receiving Desflurane and sevoflurane respectively by computer generated sequence. Standard anaesthesia induction protocol will be followed,and airway will be secured using endotracheal tube or supraglottic device, following which inhalation agent will be started according to the allotted group.
Primary objective is to see time to achieve MAC of 0.9 and eye opening following vaporizer closure whereas secondary objective is to see the hemodyamic effects, BIS value along with carbon footprints of minimal flow sevoflurane and Desflurane anaesthesia.
研究设计
- 研究类型
- Interventional
- 分配方式
- Computer generated randomization
- 盲法
- Participant Blinded
入排标准
- 年龄范围
- 18.00 Year(s) 至 65.00 Year(s)（—）
- 性别
- All
入选标准
- •Age 18-65 years
- •ASA physical status 1 and 2
- •Duration of surgery >1 hour.
排除标准
- •History of hepatic,renal,or cardiovascular disease 2.Patient with chronic obstructive pulmonary disease
- •Pregnant patient 4.Obesity (BMI >30kg/m2).
结局指标
主要结局
1.Onset time
时间窗: 1.time in seconds after intubation to acheive MAC of 0.9 | 2.time in seconds after vaporizer closure to eye opening
2.Recovery time
时间窗: 1.time in seconds after intubation to acheive MAC of 0.9 | 2.time in seconds after vaporizer closure to eye opening
次要结局
- 1.systolic blood pressure, diastolic blood pressure, heart rate and Spo2(2.Bispectral index)