Comparative Study of Training Modality After Myocardial Infarction; Standard Care Rehabilitation Training or Interval Treadmill Training
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 89
- 试验地点
- 3
- 主要终点
- change in maximal oxygen consumption
研究概览
简要总结
The purpose of this study is to investigate the effect of the standard rehabilitation offered by three hospital rehabilitation units in Norway, one in Trondheim, one in Ålesund and one in Levanger, compared to an interval treadmill training program. The subjects participating in the study are patients with myocardial infarction. The maximal oxygen consumption of the subjects will be tested before and after the training period.
详细描述
The purpose of this study is to investigate the effect of the standard rehabilitation offered by three hospital rehabilitation units in Norway, one in Trondheim, one in Ålesund and one in Levanger, compared to an interval treadmill training program. The subjects participating in the study are patients with myocardial infarction. The maximal oxygen consumption of the subjects will be tested before and after the training period.
Primary outcome: Maximal oxygen consumption Secondary outcomes: Blood values (for endothelial function, blood lipids, etc), flow mediated dilatation, quality of life (SF 36 and MacNew), weight, BMI, heart rate fall 1 minute after stopping the maximal treadmill test.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 90 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Myocardial infarction 2-12 weeks ago
排除标准
- •Heart failure
- •limitations to walking on a treadmill
- •failure to reach a maximal pre-test(> NYHA class II)
- •uncontrolled hypertension
- •pregnancy
- •kidney failure (creatinin > 140)
- •drug abuse
- •left ventricle EF < 30%
研究组 & 干预措施
1
Standard exercise training rehabilitation at the hospital
干预措施: Exercise training (Behavioral)
2
Interval exercise training on treadmills, with high intensity
干预措施: Exercise training (Behavioral)
结局指标
主要结局
change in maximal oxygen consumption
时间窗: baseline, after intervention and at 6 months
At baseline, following intervention and at 6 months after the intervention. An additional follow-up test will be conducted in all patients who want to participate during 2009.
次要结局
- quality of life(baseline, after intervention and at 6 months)
- flow mediated dilatation(baseline, after intervention and at 6 months)
- echocardiography(baseline, after intervention and at 6 months)
- blood markers(baseline, after intervention and at 6 months)