NCT02919709Unknown不适用
Follow up of Patients With Aortic Aneurysm by Dosage of Circulant Endothelial Progenitor Cells
适应症
干预措施
试验速览
- 阶段
- 不适用
- 入组人数
- 40
- 试验地点
- 1
- 主要终点
- progenitor cells CD34+ blood levels
研究概览
简要总结
The study aims to investigate the existence of a reliable correlation between the progression of aortic diameters and blood levels of circulant endothelial progenitor cells CD34+ in patients with not surgical aortic aneurysms.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Prevention
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients aged 18 or more.
- •Patients diagnosed with a thoracic or abdominal aortic aneurysm with no indication for surgical treatment (diameters > 30 mm but < 50 mm).
- •Patients accepting to sign a specific informed consent.
排除标准
- •Unstable coronary artery disease.
- •Congenital heart disease.
- •Any evolving infectious syndrome or viral infection (HIV, HBV or HCV).
- •Any chronic inflammatory or autoimmune disease.
- •Prior administration of G-CSF; EPO; GM-CSF.
- •Liver failure.
- •Prior oncologic disease or ongoing cancer with a life expectancy < 1 year.
- •Patients aged < 18.
研究组 & 干预措施
thoracic or abdominal aortic aneurysm
Experimental
干预措施: blood taking (Biological)
结局指标
主要结局
progenitor cells CD34+ blood levels
时间窗: 24 month after diagnosis
progenitor cells CD34+ blood levels
时间窗: At diagnosis of aneurysm
progenitor cells CD34+ blood levels
时间窗: 6 month after disgnosis
progenitor cells CD34+ blood levels
时间窗: 12 month after diagnosis
progenitor cells CD34+ blood levels
时间窗: 18 month after diagnosis
次要结局
未报告次要终点
研究者
研究点 (1)
Loading locations...
相似试验
招募中
不适用
Diagnosis and Prognosis for Aortic Aneurysm aNd Dissection in Anzhen(DPANDA) StudyAortic AneurysmAortic DissectionNCT03233087Beijing Institute of Heart, Lung and Blood Vessel Diseases1,500
招募中
不适用
Progression of Ascending Aorta Diameters in Bicuspid Aortic Valve After Transcatheter or Surgical Replacement.Bicuspid Aortic ValveAortic Valve StenosisAscending Aorta AneurysmValvular Heart DiseaseHeart DiseasesValvular Aortic StenosisAortic AneurysmNCT05708118Fondazione Policlinico Universitario Agostino Gemelli IRCCS150
招募中
不适用
Clinical Characteristics and Prognosis of Aortic Dissection in China (CLASSIC)Aortic DissectionNCT05999188First Affiliated Hospital Xi'an Jiaotong University100
招募中
不适用
Changes of Ascending Aortic Diameter in Patients Undergoing Transcatheter Aortic Valve ReplacementAscending Aortic DilatationBicuspid Aortic ValveAortic StenosisNCT05739253China National Center for Cardiovascular Diseases480
已完成
不适用
Follow-up of Endovascular Aneurysm Treatment - The FEAT TrialAortic Aneurysm, AbdominalNCT00281411Clinical Research Office Imaging Division46