A prospective randomised trial to compare the effects early versus late Percutaneous Dilatational Tracheostomy (PTD) after incubation on the rate of Ventilator-Associated Pneumonia (VAP), mortality and other factors in critically ill patients on long-term ventilation.

niversity Hospital of Giessen (Germany)0 个研究点目标入组 100 人开始时间: 2010年2月19日最近更新: 2015年1月13日

适应症

试验速览

暂无简介。

•1. Critically-ill patients requiring ventilatory support and intubation, recruited from the following three ICUs: surgical, neurological, neurosurgical.
•2. Expected time of ventilation > 21 days
•3. Age > 18 years
•4. Informed consent that the patient may be included into the study

•1. Anatomic variants or deformities of the larynx, trachea, and collum
•2. Pre-existing tracheostomy
•3. Pre-existing pneumonia
•4. Critical trauma of the cervical vertebral column
•5. Coagulopathy (thrombocytes < 60,000 per µl, prothrombin time > 40 seconds, international normalized ratio > 1.4)
•6. Estimated to die within the next 24 h
•7. Planned permanent tracheostomy (after laryngectomy)
•8. More than 3 days of ventilation before entry into the study

发起方

niversity Hospital of Giessen (Germany)