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临床试验/NCT03159065
NCT03159065已完成不适用

Early Postprandial Efficacy of Probiotic Fruit Beverages on Glucose Tolerance and Insulin Resistance in Healthy Adults

Lund University0 个研究点目标入组 12 人开始时间: 2014年9月1日最近更新:
适应症
干预措施

试验速览

阶段
不适用
状态
已完成
入组人数
12
主要终点
Efficacy of the study products on the postprandial serum insulin

研究概览

简要总结

Consumption of polyphenol-rich fruits and vegetables may improve the postprandial glucose and insulin responses and hence promote well-being. It has previously been observed that consumption of a bilberry drink decreases the postprandial insulin demand. In the present study, the impact of probiotic fruit beverages with different polyphenol profiles on the postprandial levels of glucose and insulin, were investigated.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Crossover
主要目的
Screening
盲法
Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)

入排标准

年龄范围
18 Years 至 65 Years(Adult, Older Adult)
性别
All
接受健康志愿者
是

入选标准

  • •Healthy, not on medication, non-allergic, individuals aged 18-65 years old, having a BMI between 20-30 kg/m2 and also maintaining stable body weight, i.e. less than 5% weight change in the last three months before the study.

排除标准

  • 未提供

研究组 & 干预措施

Blackcurrant

Experimental

A blackcurrant-based beverage with fermented oatmeal

干预措施: Blackcurrant (Other)

Beetroot

Experimental

A beetroot-based based beverage with fermented oatmeal

干预措施: Beetroot (Other)

Mango

Experimental

A mango-based based beverage with fermented oatmeal

干预措施: Mango (Other)

Rose hip

Experimental

A rose hip-based based beverage with fermented oatmeal

干预措施: Rose hip (Other)

Bilberry

Experimental

A bilberry-based beverage with fermented oatmeal

干预措施: Bilberry (Other)

Glucose drink

Active Comparator

A reference glucose drink

干预措施: Glucose drink (Other)

结局指标

主要结局

Efficacy of the study products on the postprandial serum insulin

时间窗: Incremental area under the curve for serum insulin from 0 min up to 120 min following the ingestion of the study product

The postprandial incremental area under the curve for serum insulin

次要结局

  • Efficacy of the study products on the postprandial serum glucose(Incremental area under the curve for serum glucose from 0 min up to 120 min following the ingestion of the study product)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Åsa Håkansson

Associate Senior Lecturer

Lund University

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