NCT01970800撤回不适用
The Role of Igf-1 Generation Test in Diagnosis and Treatment of Short Stature
适应症
干预措施
相关药物
试验速览
- 阶段
- 不适用
- 状态
- 撤回
- 试验地点
- 1
- 主要终点
- Primary Efficacy Outcome measurement
研究概览
简要总结
The purpose of the study is to evaluate the predictive value of IGF-1 generation test for growth velocity during GH treatment for 12 months.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Other
- 盲法
- None
入排标准
- 年龄范围
- 5 Years 至 11 Years（Child）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •ability to provide written informed consent
- •Prepubertal males and females form 5- 11years old
- •Bone age <11 years in males and <9 years in females
- •Height SD score<-2.25SD in males and females
- •IGF-1SD score <-1SD in both males and females
- •Peak GH level after stimulation >10ng/ml
排除标准
- •History of prior chemotherapy and or radiation
- •Active neoplasm
- •Pediatric patients with closed epiphyses
- •Prader-Willi syndrome, Turner syndrome or any other genetic or chromosomal anomaly
- •Treatment with inhaled or systemic steroids
- •BMI <5th percentile or >95th percentile
- •Tanner 2 at clinical or biochemical examination by ultrasensitive LH and FSH
研究组 & 干预措施
Growth hormone, injections
Experimental
Growth hormone injection 0.3mg/kg/week dailY
干预措施: Growth Hormone (Drug)
结局指标
主要结局
Primary Efficacy Outcome measurement
时间窗: one year
Growth velocity after treatment with appropriate growth hormone doses
次要结局
未报告次要终点
研究者
研究点 (1)
Loading locations...
相似试验
已完成
4 期
IGF1 Generation TestGrowth Hormone DeficiencyNCT00145457Pfizer82
招募中
不适用
Efficacy of Insulin Like Growth Factor-1(IGF-1) on Bone Regeneration in Intrabony Defects : A Clinico-radiograph StudyIntrabony Periodontal DefectNCT06426524Dr R Viswa Chandra24
终止
不适用
IGF-1, IGFBP3, ALS Normative Ranges in Healthy Pediatric Spanish PopulationIGF-1 DeficiencyNCT01676090Ipsen304
Unknown
4 期
Status of Growth Hormone/ Insulin-like Growth Factor-1 (GH/IGF-1) Axis and Growth Failure in Ataxia Telangiectasia (AT)Ataxia TelangiectasiaGrowth FailureNCT01052623Johann Wolfgang Goethe University Hospital24
已完成
4 期
A Study to Optimize Growth Hormone Dosing in Children With Chronic Kidney Disease by Measuring IGF-1 Levels in BloodKidney Failure, ChronicGrowth Hormone DeficiencyNCT00212758Oregon Health and Science University17