Effect of Axial Length on Peripapillary Retinal Nerve Fibre Layer (RNFL) Using Optical Coherence Tomography (OCT)
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 80
- 主要终点
- Retinal nerve fibre layer (RNFL) thickness
研究概览
简要总结
the goal of this obsrevational study is to learn about retinal nerve fibres and if their numbers changed with axial length of the globe or not. the main question to answer is there is effect of long axial length on the thickness of the retinal nerve fibers participants will be asked to:
- measure the axial length with ultrasound
- measure the thickness of retinal nerve fibers with optical coherence tomography
详细描述
Aim of the work:
To investigate the effect of axial length on the peripapillary retinal nerve fiber layer.
Patients and methods Study design: Cross sectional comparative study. Location: Ophthalmology department, Sohag teaching hospital. Ethical approval: A written informed consent will be taken from all patients about the aim of the study, the nature of the planned investigation. An approval of the ethical committee of Sohag Faculty of Medicine will be fulfilled.
Methodology The study will include 80 patients healthy volunteers who underwent ophthalmologic examinations including retinal nerve fiber layer (RNFL) thickness analysis with optical coherence tomography (OCT), auto refraction, and axial length measurement.
Inclusion criteria:
研究设计
- 研究类型
- Observational
- 观察模型
- Other
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 18 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Healthy volunteers attending the outpatient clinic for surface ocular diseases.
- •patients who are cooperative with optical coherence tomography (OCT) device.
排除标准
- •Glaucoma patients.
- •Media opacity (corneal, lens or vitreous opacity)
- •Previous ocular surgery.
- •Diabetic patients.
- •Retinal diseases.
结局指标
主要结局
Retinal nerve fibre layer (RNFL) thickness
时间窗: average of one year
Measuring Retinal nerve fibre layer (RNFL)thickness using OCT
次要结局
未报告次要终点
研究者
Asmaa Ibrahim Mostafa
Principal Investigator, ophthalmology resident
Sohag University