The Cardio-toxicity of Cancer Chemotherapy And Anaesthesia - A Prospective Observational Study
试验速览
- 阶段
- Unknown
- 状态
- 尚未招募
- 发起方
- 入组人数
- 51
- 试验地点
- 1
- 主要终点
- - Preoperative MET level
研究概览
简要总结
Patients who have received cancer chemotherapy also experience the toxic effects of the therapy. Many studies have shown that chemotherapy induced cardiac dysfuntion is a major contributor in morbidity and mortality rate. The myocardial depressant effect of anaesthesia can exacerbate the cardoitoxic side effect of cancer chemotherapy. Various other factors like surgical pathology, extend of surgery and age related physiology are directly related to mortality. Thus, we expect that there will be an increase or development of new cardiovascular complications postoperatively
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18.00 Year(s) 至 65.00 Year(s)（—）
- 性别
- All
入选标准
- •Patients who have received cardiotoxic cancer chemotherapy.
- •Patients more than 18 years.
- •Patients of either sex.
- •ASA physical status I and II.
- •Patients posted for elective surgery.
排除标准
- •Patients with post radiotherapy.
- •Patients who have received non cardiotoxic cancer chemotherapy.
- •ASA physical status III and IV.
- •Patients with pre-existing cardiac diseases.
结局指标
主要结局
- Preoperative MET level
时间窗: Preoperative
- Preoperative chest x-ray findings
时间窗: Preoperative
- Preoperative ECG findings
时间窗: Preoperative
- Preoperative echogardiography findings
时间窗: Preoperative
次要结局
- - Postoperative MET level(- Postoperative chest x-ray findings)