NCT02187913Unknown不适用
Effects of Resistant Starch in a Baked Snack Bar on a Post-prandial Glycemic and Insulinemic Response
适应症
试验速览
- 阶段
- 不适用
- 入组人数
- 20
- 试验地点
- 2
- 主要终点
- resistant starch effects
研究概览
简要总结
- About two-thirds of adults in the United States are overweight or obese which can cause adverse health consequences for those individuals. Post-prandial hyperglycemia is one of these possible consequences and is associated with a higher risk for Type 2 Diabetes. Controlling hyperglycemia is important in the prevention of the onset of diabetes and obesity. Resistant starch is a dietary carbohydrate which is not completely digested in the gut and produces energy for the body to use. The investigators are interested in assessing the effects of resistant starch on postprandial blood glucose and insulin concentrations.
- Aim: To assess the effects of a resistant starch on post-prandial blood glucose and insulin concentrations.
- Hypothesis: A baked snack bar with a resistant starch will blunt and sustain the post-prandial rise in blood glucose and insulin concentrations compared to a baked snack bar with maltodextrin (an easily digested carbohydrate).
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Basic Science
- 盲法
- Double (Participant, Investigator)
入排标准
- 年龄范围
- 18 Years 至 29 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Thirty healthy men and women (aged 18-29y) will be recruited from the greater Lafayette, IN region with the expectation that ≥20 subjects will complete the study. Subjects must weigh >110 pounds, with a BMI between 20.0 and 29.9.
排除标准
- •Weight change > 3kg in the past 3 months
- •Exercising vigorously over the past 3 months as well as no exercise 3 days prior to testing day
- •Intestinal disorders including lipid mal-absorption or lactose intolerance
- •Abnormal liver or kidney function tests; fasting blood glucose >100mg/dL
- •Drinking more than 2 alcoholic drinks per day
- •Taking lipid-lowering medications or dietary supplements affecting plasma cholesterol concentration.
- •Subjects must not be pregnant or lactating.
结局指标
主要结局
resistant starch effects
时间窗: 2 weeks
effects of resistant starch consumption of area under the curve of blood serum glucose, insulin, and hydrogen breath testing
次要结局
未报告次要终点
研究者
Wayne Campbell
Professor
Purdue University
研究点 (2)
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