Management of Non Convulsive Status Epilepticus
试验速览
- 阶段
- 不适用
- 入组人数
- 100
- 试验地点
- 1
- 主要终点
- Number of cured patients
研究概览
简要总结
Non convulsive status epilepticus is a persistent change in behavioural and or mental process from baseline associated with continuous epileptiform activity in electroencephalograph,it occur in about 50 percent in patients with coma and convulsions and in 8-13 percent in intensive care unit patients
详细描述
Early recognition and treatment of non convulsive status epilepticus are essential to optimize response to treatment and to prevent neurological sequelae, over diagnosis and aggressive use of anticonvulsants can contribute to morbidity and mortality.It displays great diversity in response to anticonvulsants,therefore treatment in intensive care units is required for selected cases .The aetiology and clinical forms are strong predictors for the overall prognosis.Treatment is poorly understood and follows the standard regimen for convulsive status epilepticus
研究设计
- 研究类型
- Observational
- 观察模型
- Other
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 12 Months 至 18 Years（Child, Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •patients who have generalized tonic colonic convulsions and prolonged post ictal state more than 30 minutes
- •patients presented with un explained psychic or speech disorder
- •patients presented with stupor or confusion
- •Patients presented with un explained coma
排除标准
- •patients with progressive neurological disease
- •Patients with severe cerebral anoxia
- •Patients with liver or hepatic impairment
结局指标
主要结局
Number of cured patients
时间窗: An average of 1 year
Number of cured patients
次要结局
未报告次要终点
研究者
Rewaa Mohammed
Principlal investigator
Assiut University