NCT00002051已完成不适用
Double Blind Study of Thymopentin Effects on Patients With HIV-1 Infection
Immunobiology Research Institute1 个研究点 分布在 1 个国家开始时间: 2001年8月31日最近更新:
适应症
相关药物
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 试验地点
- 1
研究概览
简要总结
Examine the ability of thymopentin (Timunox) to:
Reduce the amount and/or frequency of virus isolation. Stimulate the immune system and alter the clinical findings in patients infected with HIV who do not yet have AIDS.
研究设计
- 研究类型
- Interventional
- 主要目的
- Treatment
- 盲法
- Double
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Concurrent Treatment:
- •Aerosolized pentamidine.
- •Prior Medication:
- •Aerosolized pentamidine.
排除标准
- •Co-existing Condition:
- •Patients with the following are excluded:
- •AIDS as defined by the CDC (except for those with HIV "wasting syndrome").
- •Significant hepatic disease.
- •Thrombocytopenia (< 75000 platelets/mm3).
- •Abnormal chest x-ray (indicative of active disease (opportunistic infection)) within 30 days prior to entry.
- •Hemophilia A or B or other hematologic disorders requiring current or previous administration of blood products.
- •Known hypersensitivity to thymopentin.
- •Prior Medication:
- •Excluded within 30 days of study entry:
- •Immunomodulatory or experimental therapy.
- •Excluded within 90 days of study entry:
- •Zidovudine (AZT).
- •Patients must not have:
- •AIDS as defined by the CDC (except for those with HIV "wasting syndrome").
- •Significant hepatic disease.
- •Thrombocytopenia (< 75000 platelets/mm3).
- •Patients with the following conditions are included:
- •Seropositive for HIV-1 (ELISA assay) confirmed by Western blot.
- •HIV-1 p24 antigen must be detected in supernatant fluids from co-cultures of patient's peripheral blood monocytes (PBMC) on two separate occasions.
- •HIV "wasting syndrome".
- •Must voluntarily sign consent.
- •History of intravenous drug abuse.
研究者
研究点 (1)
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