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临床试验/NCT05013021
NCT05013021已完成不适用

Sprint Interval Training (SIT) on the Endurance, Strength and Velocity Capacities of Healthy Sedentary Subjects

Centre Hospitalier Universitaire de Saint Etienne2 个研究点 分布在 1 个国家目标入组 23 人开始时间: 2021年9月27日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
23
试验地点
2
主要终点
oxygen uptake (VO2max) - ml/min/kg

研究概览

简要总结

The present study aims to analyse first, the acute effects generated by a single bout of Sprint Interval Training (SIT) and, secondly, the effects of a long-term intervention on sedentary participants.

详细描述

The main goal is to determine the optimal dose of high-intensity exercise that enhances the best physiological adaptations.

The cumulative effects of SIT, will be assessed by a series of measures placed throughout the time-course (before, after the 1st , the 2nd and the 3rd block of SIT). Those measures consist of physiological measurements (VO2max), neuromuscular capacities (force-velocity profile) the autonomic nervous system responses (heart rate variability) and blood markers (lactate, Creatine phosphoKinase (CK), cytokinases, µRNA). Acute effects will be measured in the familiarisation sessions (after short (8 sprints) and long (14 sprints) sets) by performing a battery of neuromuscular, perceptual, and autonomic nervous system tests before and after the single session of SIT.

研究设计

研究类型
Interventional
分配方式
Na
干预模型
Single Group
主要目的
Other
盲法
None

入排标准

年龄范围
18 Years 至 40 Years(Adult)
性别
All
接受健康志愿者

入选标准

  • untrained healthy (less than 2 hours of sport per week)
  • free from muscular, bone or joint injuries
  • free from neurologic disease

排除标准

  • taking neuroactive substances that can alter corticospinal excitability
  • Heart or respiratory failure.
  • Subjects who have taken corticosteroids within 3 months (inhalation, infiltration or history of corticosteroid therapy).
  • Pregnant woman
  • Subject under guardianship

结局指标

主要结局

oxygen uptake (VO2max) - ml/min/kg

时间窗: At the end of the 1st, 2nd and 3rd block : Each block = 2 weeks; each block is 1 day apart

consumption oxygen uptake (VO2max) measured on a cycle ergometer The main objective is to determine at which time frame of sprint interval training blocks, the endurance performance (VO2max) is best.

次要结局

  • Maximum theoretical speed (m/s)(At the end of the 1st, 2nd and 3rd block : Each block = 2 weeks; each block is 1 day apart)
  • Maximum power (W)(At the end of the 1st, 2nd and 3rd block : Each block = 2 weeks; each block is 1 day apart)
  • Creatine Kinase (UI/l)(At the end of the 1st, 2nd and 3rd block : Each block = 2 weeks; each block is 1 day apart)
  • heart rate variability (HRV)(At the end of the 1st, 2nd and 3rd block : Each block = 2 weeks; each block is 1 day apart)
  • Cytokines (pg/ml)(At the end of the 1st, 2nd and 3rd block : Each block = 2 weeks; each block is 1 day apart)
  • muscle microRNA(At the end of the 1st, 2nd and 3rd block : Each block = 2 weeks; each block is 1 day apart)
  • Maximum theoretical force (N.m)(At the end of the 1st, 2nd and 3rd block : Each block = 2 weeks; each block is 1 day apart)
  • Maximum isometric force (N.m)(At the end of the 1st, 2nd and 3rd block : Each block = 2 weeks; each block is 1 day apart)
  • Lactate (mmol/l)(At the end of the 1st, 2nd and 3rd block : Each block = 2 weeks; each block is 1 day apart)

研究者

申办方类型
Other
责任方
Sponsor

研究点 (2)

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