Natural History and Patient Journey in Dementia: a Nationwide Linked Electronic Health Records Study of 5.6 Million Individuals.

University College, London0 个研究点目标入组 4,309,481 人开始时间: 1998年1月1日最近更新: 2020年11月13日

适应症

试验速览

阶段: 不适用
发起方: University College, London
入组人数: 4,309,481
主要终点: Incidence and mortality of dementia

研究概览研究设计入排标准结局指标研究者记录与标识符相似试验

研究概览

简要总结

The trajectory of dementia patients within the national health system and their recent temporal trends remains to be fully elucidated. To study the dementia incidence, mortality and case-fatality, we implemented a longitudinal cohort study with the linked electronic health records of 5.6 million population in the UK from 1998 to 2016 (CALIBER). A matched case-control study design was used to investigate the causes of hospitalization and death comparing individuals with and without incident dementia.

研究设计

研究类型: Observational
观察模型: Cohort
时间视角: Prospective

入排标准

年龄范围: 30 Years 至 —（Adult, Older Adult）
性别: All
接受健康志愿者: 是

入选标准

•We identify individuals aged 30 years or older and registered in the current primary care practice for at least one year.

排除标准

•Individuals are excluded if they had a prior history of dementia before study entry.

结局指标

主要结局

Incidence and mortality of dementia

时间窗: Jan 1st 1998 - May 31st 2016

次要结局

未报告次要终点

研究者

发起方

University College, London

申办方类型

Other

责任方

Sponsor

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