Antibiotic Use in a Neonatal Intensive Care Unit Practicing Integrative Medicine
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 246
- 试验地点
- 1
- 主要终点
- Antibiotic prescription rate
研究概览
简要总结
The goal of this study is to describe the antibiotic use in a neonatal intensive care unit (NICU) in Germany that is practising integrative medicine. The investigators will review hospital records to find out how often and how long antibiotics were given to newborns; compare antibiotic use to other NICU in the same area; describe how sick infected newborns were (comparing those treated with or without antibiotics); and describe which anthroposophic medicines were used, how often and if there were safety problems.
详细描述
A retrospective study, analysing antibiotic use in a level 2 neonatology intensive care unit (NICU) in Germany over a 4-year period from 2014 to 2017. The study will analyse frequency of antibiotic prescribing; compare antibiotic use to other level 2 NICU; compare clinical and laboratory parameters among neonates with infectious disease diagnosis managed with or without antibiotics; use and tolerability of anthroposophic medicinal products.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 0 Days 至 30 Days（Child）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Admission to neonatal intensive care unit
排除标准
- 未提供
结局指标
主要结局
Antibiotic prescription rate
时间窗: January 1, 2014 to December 31, 2017
Number of antibiotic treatment days per 100 hospital days
次要结局
- Antibiotic treatment duration(January 1, 2014 to December 31, 2017)
- Clinical and laboratory parameters in neonates with infectious disease diagnosis: Mother group B streptococcus positive(January 1, 2014 to December 31, 2017)
- Clinical and laboratory parameters in neonates with infectious disease diagnosis: Low birthweight(January 1, 2014 to December 31, 2017)
- Clinical and laboratory parameters in neonates with infectious disease diagnosis: Infant fever on admission(January 1, 2014 to December 31, 2017)
- Clinical and laboratory parameters in neonates with infectious disease diagnosis: CRP maximum value(January 1, 2014 to December 31, 2017)
- Use of anthroposophic medications: frequency of use(January 1, 2014 to December 31, 2017)
- Clinical and laboratory parameters in neonates with infectious disease diagnosis: Premature rupture of membranes(January 1, 2014 to December 31, 2017)
- Clinical and laboratory parameters in neonates with infectious disease diagnosis: Leukocyte count maximum value(January 1, 2014 to December 31, 2017)
- Safety of anthroposophic medications: adverse drug reactions(January 1, 2014 to December 31, 2017)
- Antibiotic use compared to other level 2 NICU in same geographic area(January 1, 2014 to December 31, 2017)
- Clinical and laboratory parameters in neonates with infectious disease diagnosis: pH umbilical artery at birth(January 1, 2014 to December 31, 2017)
- Antibiotic type(January 1, 2014 to December 31, 2017)
- Use of anthroposophic medications: medication names(January 1, 2014 to December 31, 2017)
- Safety of anthroposophic medications: side effects(January 1, 2014 to December 31, 2017)