NCT04125199已完成不适用
Effects of Decohexaenoic Acid Supplementation on Markers of Inflammatory Muscle Damage Induced by Eccentric Exercise in Endurance Athletes
Universidad Católica San Antonio de Murcia2 个研究点 分布在 1 个国家目标入组 15 人开始时间: 2016年1月1日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 15
- 试验地点
- 2
- 主要终点
- Inflammatory markers
研究概览
简要总结
Randomized, placebo-controlled, double-blind, placebo-controlled clinical trial consisting of 15 triathletes in which it is intended to observe less inflammatory damage at the muscular level after performing eccentric exercises.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Prevention
- 盲法
- Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 45 Years（Adult）
- 性别
- Male
- 接受健康志愿者
- 是
入选标准
- •Male sex.
- •Age: between 18 and 45 years.
- •BMI ≤ 35 Kg / m
- •Volunteers capable of understanding the clinical study, competent to grant written informed consent and willing to comply with the study procedures and requirements.
- •Subjects who do not suffer from chronic diseases.
- •Non-smoking subjects or less than 10 cigarettes a day.
- •Subjects who have not consumed any type of NSAID within 48 hours prior to the study or during its development.
- •Subjects without a history of administration of corticosteroids the previous month or during the study.
- •Subjects without allergy to any of the products under investigation.
- •Patients who have not modified their habits in the performance of physical activity during the study (injuries, injuries ...).
- •Patients who have not modified their dietary habits during the previous month or intend to do so during the study.
排除标准
- •Subjects who do not consume medication or nutritional supplements with antioxidant and / or anti-inflammatory properties.
- •Subjects who do not consume diets with abundant antioxidant and / or anti-inflammatory products.
结局指标
主要结局
Inflammatory markers
时间窗: It was measured before and after consumption of the supplement. In each of the times it was measured four times. Before performing the eccentric exercises, just after, at 24 and 48 hours later.
Changes in the inflammatory marker: C-reactive protein (ml / dl). It is measured in venous blood by blood extraction.
次要结局
- Hematological variables: LEUCOCITS AND PLATES(It was measured before and after supplement consumption. In each of the times it was measured four times. 1: before performing the eccentric exercises, 2: just after, 3: at 24 hours after and 4: 48 hours later.)
- connective tissue injury(It was measured before and after consumption of the supplement. In each of the times it was measured four times. Before performing the eccentric exercises, just after, at 24 and 48 hours later.)
- muscle damage(It was measured before and after consumption of the supplement. In each of the times it was measured four times. Before performing the eccentric exercises, just after, at 24 and 48 hours later.)
- Biochemical variables(It was measured before and after consumption of the supplement. In each of the times it was measured four times. Before performing the eccentric exercises, just after, at 24 and 48 hours later.)
- Isokinetic variables(Twice. One, before the consumption of the product under study and another after the consumption of the product. It was measured after 10 weeks.)
- Anthropometric variables(Two measurements. One, before the consumption of the product under study and another at 8 weeks of product consumption.)
- Impedancemetric variables(Two measurements. One, before the consumption of the product under study and another at 8 weeks of product consumption.)
- liver safety variables(It was measured before and after consumption of the supplement. In each of the times it was measured four times. Before performing the eccentric exercises, just after, at 24 and 48 hours later. One year)
- Variable for the evaluation of fatigue: Subjective perception test of Borg's effort(at the end of the stress test with the multipower. It was measured three times. 1: at the end of the test, 2: at 24 hours, 3: at 48 hours.)
- Perception of pain through the analog visual scale.(at the end of the stress test with the multipower. It was measured three times. 1: at the end of the test, 2: at 24 hours, 3: at 48 hours.)
研究者
Francisco Javier López Román
Principal Investigator
Universidad Católica San Antonio de Murcia
研究点 (2)
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