The Application of Butorphanol in Postoperative Analgesia Management After Cesarean Section: A Retrospective Cohort Study
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 2,500
- 主要终点
- Pain Score
研究概览
简要总结
This study explored the association between postoperative functional recovery and the formula of analgesic pumps as well as other related factors (such as age, intraoperative blood loss, operation duration, etc.) by retrospectively analyzing the clinical data of patients undergoing cesarean section in the main campus and branches of Sichuan Provincial People's Hospital from September 2024 to June 2025. The value of this study lies in: 1) providing a basis for optimizing the postoperative analgesia plan after cesarean section. 2) To provide references for the formulation of personalized analgesia strategies in clinical practice, improve the postoperative recovery quality of patients, promote the concept of enhanced recovery after surgery, and reduce the medical burden.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 55 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •Age 18-55 years
- •ASAI-III level
- •Scheduled or emergency cesarean section
- •Postoperative use of analgesic pump (formulation includes buprenorphine or tramadol or hydromorphone, etc.)
- •Complete electronic medical records
排除标准
- •Postoperative analgesia pump usage time is less than 24 hours
- •Missing key information such as follow-up status in medical records
研究组 & 干预措施
The group using the analgesic pump
干预措施: An postoperative analgesic pump was used (Drug)
结局指标
主要结局
Pain Score
时间窗: 2 days post-surgery
The Visual Analog Scale (VAS) is primarily used, where 1 represents no pain (best outcome) and 10 represents the worst pain (worst outcome); other scales may be used if necessary.
Postoperative functional recovery status
时间窗: 2 days post-surgery
Postoperative functional recovery status mainly includes: the time of first passage of gas, the time of first ambulation, the time of first catheter removal, and the recovery of limb muscle strength. The passage of gas, ambulation, and catheter removal times are self-reported by the patients, recording the days after surgery when the events occurred. The recovery of limb muscle strength is classified into six levels, ranging from 0 to 5, where 0 indicates no detectable muscle contraction (worst outcome) and 5 indicates normal muscle strength (best outcome).
Sedation score
时间窗: 2 days post-surgery
The sedation score uses a scale from -5 to +4, where -5 is defined as coma (one of the worst outcomes); -4 is defined as severe sedation (responds to physical stimulation); -3 is moderate sedation (no response to auditory stimulation); -2 is mild sedation (unable to maintain alertness for more than 10 seconds); -1 is drowsiness (not fully awake but can stay awake for more than 10 seconds); 0 is the awake natural state (best outcome); +1 is restlessness and anxiety (anxious and tense, but only slight body movement); +2 is agitation and anxiety (intense body movement); +3 is very agitated (trying to remove body tubes); +4 is aggressive (violent behavior) (one of the worst outcomes).
次要结局
- Overall patient satisfaction rating(2 days post-surgery)
- Nausea and vomiting(2 days post-surgery)
- Adverse reactions(2 days post-surgery)
研究者
Yanyu Liu
Physician-in-charge
Sichuan Provincial People's Hospital